Screening for antisperm antibodies should not be offered because there is no evidence of effective treatment to improve fertility. Women who are concerned about their fertility should not be offered a blood test to measure prolactin. This test should only be offered to women who have an ovulatory disorder, galactorrhoea or a pituitary tumour. Women with possible fertility problems are no more likely than the general population to have thyroid disease and the routine measurement of thyroid function should not be offered. Estimation of thyroid function should be confined to women with symptoms of thyroid disease.
Antisperm antibodies are antibodies produced against sperm antigens. ASA can be detected in ejaculate, cervical mucus, follicular fluid, and blood serum. ASA can arise whenever sperm encounter the immune system. However, these antibodies are also present in approximately 1—2.
Importance in the clinical routine for the diagnosis of immunologically caused fertility disorders
Jump to content. An antisperm antibody test looks for special proteins antibodies that fight against a man's sperm in blood, vaginal fluids, or semen. The test uses a sample of sperm and adds a substance that binds only to affected sperm. Semen can cause an immune system response in either the man's or woman's body.
Infertility is one of the common problems seen in couples of reproductive age. Presence of antisperm antibodies in semen and serum are amongst the causes of immunoinfertility. This study was performed to determine antisperm antibodies in cervicovaginal secretions and serum of infertile women and also measure serum levels of immunoglobulins IgG, IgM and IgA. The study consisted of 45 infertile women consulting the Kammal El-Sammrari Hospital for infertility from to and the control group consisted of 30 fertile women. Serum levels of immunoglobulins IgG, IgA and IgM were measured in the participants using single radial immune diffusion.